{
  "schema_version": 1,
  "topic_id": "sleep-circadian",
  "topic_title": "Sleep & Circadian Rhythm",
  "domain_id": "health-energy",
  "domain_title": "Health & Energy",
  "ontology_status": "growth-gap",
  "baseline_status": "growth-gap",
  "question": "Which modifiable sleep-timing or regularity behaviors have causal evidence for meaningful daytime outcomes?",
  "evidence_target": "Prefer intervention studies and high-quality reviews that distinguish association from causal behavior change.",
  "guardrail": "No fixed bedtime tolerance or medical sleep prescription should be inferred from observational associations.",
  "stage": "ready-for-resolution",
  "stage_label": "Ready for resolution review",
  "stage_summary": "A reviewed Evidence Decision and trusted Topic protocol exist, but no explicit closure record exists yet.",
  "canonical_url": "https://brali-lifeos.github.io/research/gaps/sleep-circadian/",
  "research_queries": [
    {
      "id": "health-sleep-regularity",
      "query": "sleep regularity health behavior systematic review adults",
      "risk_flags": [
        "health"
      ]
    }
  ],
  "candidates": [
    {
      "id": "crossref:10.1016/j.jad.2025.120481",
      "title": "The association between sleep variability and cognitive function: A systematic review and meta analysis",
      "status": "watch",
      "publication_date": "2026-01-15",
      "reference_url": "https://doi.org/10.1016/j.jad.2025.120481"
    },
    {
      "id": "crossref:10.1016/j.smrv.2021.101532",
      "title": "Behavioral interventions to extend sleep duration: A systematic review and meta-analysis",
      "status": "propose-protocol",
      "publication_date": "2021-12-01",
      "reference_url": "https://doi.org/10.1016/j.smrv.2021.101532"
    },
    {
      "id": "crossref:10.1093/sleep/zsae230",
      "title": "Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial",
      "status": "support-existing",
      "publication_date": "2025-04-11",
      "reference_url": "https://doi.org/10.1093/sleep/zsae230"
    },
    {
      "id": "crossref:10.3389/fpubh.2026.1906525",
      "title": "The effects of progressive muscle relaxation on sleep quality in adults: a systematic review and meta-analysis of randomized controlled trials",
      "status": "support-existing",
      "publication_date": "2026-08-06",
      "reference_url": "https://doi.org/10.3389/fpubh.2026.1906525"
    }
  ],
  "evidence_decisions": [
    {
      "id": "caffeine-dose-timing-sleep-boundary-2025",
      "decision": "support-existing",
      "reviewed_at": "2026-09-06",
      "source_title": "Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial",
      "ledger_url": "https://brali-lifeos.github.io/evidence/caffeine-dose-timing-sleep-boundary-2025/"
    },
    {
      "id": "pmr-subjective-sleep-quality-boundary-2026",
      "decision": "support-existing",
      "reviewed_at": "2026-09-11",
      "source_title": "The effects of progressive muscle relaxation on sleep quality in adults: a systematic review and meta-analysis of randomized controlled trials",
      "ledger_url": "https://brali-lifeos.github.io/evidence/pmr-subjective-sleep-quality-boundary-2026/"
    },
    {
      "id": "sleep-opportunity-extension-2021",
      "decision": "propose-protocol",
      "reviewed_at": "2026-08-19",
      "source_title": "Behavioral interventions to extend sleep duration: A systematic review and meta-analysis",
      "ledger_url": "https://brali-lifeos.github.io/evidence/sleep-opportunity-extension-2021/"
    },
    {
      "id": "sleep-variability-cognition-2026",
      "decision": "watch",
      "reviewed_at": "2026-08-18",
      "source_title": "The association between sleep variability and cognitive function: A systematic review and meta analysis",
      "ledger_url": "https://brali-lifeos.github.io/evidence/sleep-variability-cognition-2026/"
    }
  ],
  "trusted_protocols": [
    {
      "slug": "stop-caffeine-after-lunch",
      "title": "Move Caffeine Earlier When Sleep Matters",
      "url": "https://brali-lifeos.github.io/life-os/stop-caffeine-after-lunch/",
      "evidence_status": "reviewed"
    },
    {
      "slug": "ideal-sleep-hours-finder",
      "title": "Protect Enough Sleep Opportunity and Track Daytime Function",
      "url": "https://brali-lifeos.github.io/life-os/ideal-sleep-hours-finder/",
      "evidence_status": "reviewed"
    }
  ],
  "resolution": null,
  "coverage": {
    "id": "sleep-circadian",
    "title": "Sleep & Circadian Rhythm",
    "domain_id": "health-energy",
    "status": "growth-gap",
    "entries": 2,
    "research_candidates": 4
  }
}